Cholibrium Review: Ingredients, Evidence, Price & Safety
An independent evidence-aware review of Cholibrium, including verified manufacturer facts, current pricing, ingredient evidence, limitations and safety considerations.
Our bottom line
Cholibrium is a 10-mushroom dietary supplement sold by Simple Promise. The manufacturer positions it as a heart-health and antioxidant formula. Our view is more restrained: the formula contains recognizable mushroom ingredients with published research around individual mushrooms, but ingredient research is not the same as a clinical trial of Cholibrium itself.
Verified product facts
- Manufacturer: Simple Promise
- 10 mushroom ingredients listed by the manufacturer
- Recommended use on the manufacturer page: two capsules per day with a meal and water
- Manufacturer lists a 365-day money-back guarantee and free U.S. shipping
- Current one-time pricing shown by the manufacturer: $59 for one bottle, $49/bottle for three, $39/bottle for six
Pricing and terms can change, so verify the checkout page before ordering. Source: Simple Promise product page.
What the evidence can—and cannot—tell us
Research exists on individual medicinal mushrooms, but it varies substantially in quality and relevance. A Cochrane review of Reishi for cardiovascular risk factors included only a handful of trials and did not establish a robust clinical benefit. A small randomized trial of shiitake food bars in adults with borderline-high cholesterol reported a triglyceride reduction after 66 days, but that intervention and dose are not equivalent to Cholibrium.
A broader review also cautions that traditional use and laboratory findings should not be treated as proof that mushroom preparations treat human disease. That is why Mushroom Measure does not score Cholibrium as “clinically proven” for lowering cholesterol.
Pros and tradeoffs
Potential positives
Convenient multi-mushroom format, clear ingredient list on the manufacturer page, vegan positioning, and a long stated return window.
Important limitations
No product-specific randomized clinical trial was located in our research. A blend also makes it harder to know whether each ingredient is present at a research-relevant amount unless exact extract quantities are disclosed on the label.
Medication caution
The manufacturer itself advises speaking with a doctor if you take statins, blood-pressure medications, or blood thinners.
Price and value
At the manufacturer’s current one-time pricing, larger bundles reduce the per-bottle price. Do not buy more bottles solely because of a countdown or scarcity message; choose a quantity based on your budget, return terms, and clinician guidance.
| Package | Manufacturer price | Approx. total |
|---|---|---|
| 1 bottle | $59 | $59 |
| 3 bottles | $49/bottle | $147 |
| 6 bottles | $39/bottle | $234 |
Want to check today’s Cholibrium offer?
Your purchase is completed on the merchant/ClickBank checkout, not on Mushroom Measure. Verify current price, shipping, ingredients, and return terms before paying.
Check the current Cholibrium offer